INJE PharmacoGenomics Research Center

· Kim HJ, Yoon YJ, Kim HM, Cha EY, Lee HS, Kim JH, Yi KY, Lee SK, Cheon HG, Yoo SE, Lee SS, Shin JG, Liu KH

In Vitro Metabolism of a New Cardioprotective Agent, KR-33028 in the Human Liver Microsomes and Cryopreserved Human Hepatocytes (FRONTIER)

Arch Pharm Res Vol 28, No 11, 1287-1292, 2005 [LINK]

2005-Domestic

· Kim MJ, Kim H, Cha IJ, Park JS, Shon JH, Liu KH, Shin JG.

High-throughput screening of inhibitory potential of nine cytochrome P450 enzymes in vitro using liquid chromatography/tandem mass spectrometry. (NRL)

Rapid Commun Mass Spectrom. 2005;19(18):2651-2658 [LINK]

2005-International

· Shon JH, Yoon YR, Hong WS, Nguyen PM, Lee SS, Choi YG, Cha IJ, Shin JG.

Effect of itraconazole on the pharmacokinetics and pharmacodynamics of fexofenadine in relation to the MDR1 genetic polymorphism (NRL)

Clin Pharmacol Ther. 2005;78(2):191-201. [LINK]

2005-International

· Cho MJ, Gwak JG, Park SY, Won JJ, Kim DE, Yea SS, Cha IJ, Kim TK, Shin JG, Oh S.

Diclofenac attenuates Wnt/b-catenin signaling in colon cancer cells by activation of NF-kB ()

FEBS Letters, 2005, 579/4213~4218 [LINK ]

2005-International

· Lee SS, Kim SY, Kim WY, Thi-Le H, Yoon YR, Yea SS, Shin JG.

MDR1 Genetic Polymorphisms and Comparison of MDR1 Haplotype Profiles in Korean and Vietnameses Populations (NRL)

Ther Drug Monit, 2005; 27(4):531-535. [LINK]

2005-International

· Shon JH, Yoon YR, Kim MJ, Kim KA, Lim YC, Liu KH, Shin DH, Lee CH, Cha IJ, Shin JG.

Chlorpropamide 2-hydroxylation is catalysed by CYP2C9 and CYP2C19 in vitro: chlorpropamide disposition is influenced by CYP2C9, but by CYP2C19 genetic polymorphism (NRL)

Br J Clin Pharmacol, 2005, 59/552~563 [LINK]

2005-International

· Lee SS, Kim KM, Thi-Le H, Yea SS, Cha IJ, Shin JG.

Genetic Polymorphism of CYP2C9 in a Vietnamese Kinh Population (NRL)

Ther Drug Monit, 2005, 27/208~210 [LINK]

2005-International

· Liu KH, Kim MJ, Shon JH, Moon YS, Seol SY, Kang W, Cha IJ, Shin JG.

Stereoselective inhibition of cytochrome P450 forms by lansoprazole and omeprazole in vitro (NRL)

Xenobiotica, 2005, 35/27~38 [LINK]

2005-International

· Lee SS, Jeong HE, Liu KH, Ryu JY, Moon T, Yoon CN, Oh SJ, Yun CH, Shin JG.

Identification of functional characterization of nover CYP2J2 variants: G312 variant cuases loss of enzyme catalytic activity (NRL)